Over the last decade, researchers found an increase in the number of young patients diagnosed with colorectal cancer, and often, with a more advanced stage of the disease. As a result of this trend in the wrong direction, in 2021, the U.S. Preventive Services Task Force lowered the age of colorectal cancer screening from 50 to 45 years of age, believing that doing so would help lower the risk of death from colorectal cancer in this younger age group. For example, on average, the five-year survival rate for colorectal cancer in early stages is above 90%. The change in screening guidelines has led to a significant increase in early-stage diagnosis among those in the 45-49 years old range, and that is good news.
On the question about whether screening is necessary for everyone starting at age 45, when there are no symptoms, the answer is yes. Indeed, that is the very definition of screening, which is testing done when there are no symptoms.
There are some special groups of patients to which screening may occur before age 45 years of age. For example, patients with a family history of colon cancer affecting family members at a young age, of patients with a personal history of inflammatory bowel disease such as ulcerative colitis or Crohn’s disease.
Others in the higher risk category are Black Americans and Native Americans as research shows they experience disproportionately higher rates of colon cancer incidence and mortality compared to other racial and ethnic groups. In addition, there are other known risks, such as being overweight and smoking, and for this reason, it’s important to talk with your doctor or healthcare professional, because they will be able to factor in your full health history and provide you with a recommendation for screening.
Screening for colon cancer detects pre-cancerous growths called polyps in the colon. Removal of these polyps during the colonoscopy removes the opportunity for that polyp to grow into a colon cancer. One other point on the importance of following screening guidelines is that colon polyps don’t usually cause symptoms, and that is why it is so important to find them and remove them early.